Note that all times are in UK local time (BST)
Diamond Biological Cryo-imaging User Meeting: eBIC & B24
Session 1:
On demand video link includes Session 1 & 2 recordings.
13:00
Welcome
Martin Walsh
(Diamond)
13:10
eBIC user updates
Kyle Morris
(eBIC Diamond)
13:40
Structural insights into the nuclear import of mammalian proteasomes
David Haselbach
IMP Vienna
14:10
Mechanism of dynein-2 in intraflagellar transport
Katerina Toropova
Birkbeck
14:40
Break
Session 2
On demand video link includes Session 1 & 2 recordings.
15:30
B24 user updates
Chidinma Okolo
(B24 Diamond)
16:00
Integrative imaging of SARS-CoV-2 infection
Luiza Mendonca
Oxford
16:30
User meeting round-table discussion
Chairs: Natasha Lukoyanova (Birkbeck) & Jamie Blaza (York) During the user meeting eBIC representatives will discuss topics raised in the eBIC User Survey.
17:15
Close
19:00
Informal conference dinner
Pizza & beer mixer
CCP-EM Spring Symposium VIII
Nottingham EMCC
Session 1:
On demand video link includes Session 1 & 2 recordings.
9:00
Opening and welcome
Matt Iadanza
What’s new in CCP-EM, eBIC, RFI & EMDB/EMPIAR/CCP-EM
9:30
eBIC
Karen Davies
10:00
RFI
Michael Grange
10:30
EMDB/EMPIAR
Gerard Kleywegt
11:00
Coffee
Session 2:
On demand video link includes Session 1 & 2 recordings.
11:30
RELION 4 and beyond – Structural heterogeneity and algorithmic robustness
Dari Kimanius
MRC-LMB
12:00
Map post-processing with DeepEMhancer
Ruben Sanchez-Garcia
Oxford
12:30
Zernikes3D: Analysis of conformational landscapes from CryoEM data
David Herreros
National Central for Biotechnology, CSIC
12:50
Lunch
Session 3:
14:30
The physical origins of specimen movement in electron cryomicroscopy
Katerina Naydenova
MRC-LMB
15:00
Towards Microsecond Time-Resolved Cryo-Electron Microscopy
Ulrich Lorenz
EPFL
15:30
Structural diversity of GABA(A) receptors
Andrija Sente
MRC – Laboratory of Molecular Biology
15:50
Coffee
Session 4:
16:30
New methods for preparing, imaging and processing cryo-EM samples
Tim Grant
UW-Madison
17:00
Overview of recent developments for tools in Phenix for cryo-EM
Dorothee Liebschner
Berkeley Lab
17:30
Progress and Problems in cryo-EM Validation
Peter Rosenthal
Crick
19:00
Conference dinner
Session 5:
On demand video link includes Session 5 & 6 recordings.
9:00
Cryo-electron tomography and subtomogram averaging for structural determination of membrane coat complexes
Giulia Zanetti
Birkbeck
9:30
Cryo-electron tomography workflows to extract quantitative and geometrical information from variable protein assemblies
Florian Schur
IST-Austria
10:00
Capturing Inhibited Assemblies of the Membrane Attack Complex by CryoEM
Emma Couves
Imperial College, London
10:20
Coffee
Session 6:
On demand video link includes Session 5 & 6 recordings.
11:10
Automated data acquisition for high-resolution tomography and subtomogram averaging
Wim Hagen
EMBL
11:40
Single particle cryoEM pipelines (reasons to be optimistic)
Rebecca Thompson
Leeds
12:10
Using cryo-EM of SARM1 to help design new therapeutics against neurodegenerative disease
Katie Cunnea
Evotec
12:30
Lunch
Session 7:
14:00
How to deal with large and dynamic macromolecular complexes
Holger Stark
MPI Biophysical Chemistry
14:30
Discovery of a druggable pocket and a drug in SARS-CoV-2 spike glycoprotein
Christiane Berger-Schaffitzel
Bristol
15:00
Cryo-EM structures of the deltaretroviral intasome in complex with the host factor Protein Phosphatase 2A subunit B56γ and HIV integrase inhibitors
Goedele Maertens
Imperial
15:30
A conserved mechanism for regulating replisome disassembly revealed by cryo-EM
Tom Deegan
Glasgow
16:00
Meeting close